High theophylline levels

Author: mmyn

August undefined, 2024

WebFactor which increase the half life include heart failure, cirrhosis, viral infection and drugs like cimetidine, ciprofloxacin, erythromycin and the oral contraceptive pill. The half life is decreased by smoking, heavy drinking and drugs like phenytoin, carbamazepine, rifampicin and barbiturates. WebJul 22, 2024 · The molecular formula of anhydrous theophylline is C 7 H 8 N 4 O 2 with a molecular weight of 180.17. Theo-24 is available as capsules intended for oral administration, containing 100 mg, 200 mg, 300 mg, or 400 mg of anhydrous theophylline per capsule, in an extended-release formulation which allows a 24-hour dosing interval for …

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WebThe adverse effects of theophylline include: Gastrointestinal disorders such as nausea, vomiting, gastro-oesophageal reflux. Neurological disorders such as tremor, headache, dizziness, central nervous system stimulation, insomnia, and convulsion (rare). Psychiatric disorders such as anxiety. WebMar 22, 2024 · Theophylline: Although causality has not been established, concurrent use of pentoxifylline with theophylline has resulted in elevated theophylline plasma levels, which may enhance the possibility of adverse effects. Drug-Food Interactions. Interactions with food have not been established. Drug-Herb Interactions simple white fruitcake

Theophylline - StatPearls - NCBI Bookshelf

WebMar 1, 2024 · At serum Theophylline concentrations > 20 mcg/mL, both the frequency and severity of adverse reactions increase. In general, maintaining peak serum Theophylline concentrations between 10 mcg/mL and 15 … WebHigh-carbohydrate, low-protein diets can increase theophylline activity and side effects. Sustained-release forms of theophylline should be taken on an empty stomach and should not be crushed or chewed. Liquid and non-sustained release theophylline products are best taken on an empty stomach, but they may be taken with food if stomach upset occurs. WebFeb 10, 2024 · The reference therapeutic ranges of theophylline are listed below. Reference ranges of theophylline in the treatment asthma vary by age, as follows: Adults: 5-15 µg/mL. Children: 5-10 µg/mL. The... The assessment and diagnosis of exercise-induced bronchoconstriction is made … rayleigh speedway history

Theophylline American Journal of Respiratory and Critical Care Medicine

Theophylline Toxicity – Overdoseinfo.com

WebSixty patients with theophylline toxicity were hospitalized during a 2-year period. Eleven patients had hypercalcemia; their calcium levels returned to normal as theophylline levels … WebToxic side effects of elevated theophylline levels range from minor symptoms to life-threatening complications. We investigated the incidence of life-threatening events in … rayleigh southend-on-sea united kingdomWebTheophylline levels In most individuals a plasma theophylline of between 10-20mg/litre is required for satisfactory bronchodilation; however, a lower plasma theophylline … rayleigh speedway

"WebTheophylline levels may be modestly altered in thyroid dysfunction. In hyperthyroidism, theophylline metabolism is increased, and therefore the dose may need to be reduced as thyroid levels are corrected. Conversely, patients with hypothyroidism may need the dose of theophylline increased as treatment with levothyroxine or liothyronine continues. " - High theophylline levels

High theophylline levels

WebIn most individuals, a plasma-theophylline concentration of 10–20 mg/litre (55–110 micromol/litre) is required for satisfactory bronchodilation, although a lower plasma … WebTheophylline in overdose can cause vomiting (which may be severe and intractable), agitation, restlessness, dilated pupils, sinus tachycardia, and hyperglycaemia. More …

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WebJun 30, 2024 · Adults are may be given about 300-600mg of Theophylline per day depending on their condition. This amount is equivalent to the therapeutic dose which is between 10-20mg/L. If the amount of 25mg/L, it … WebNo food or liquid (other than water) was allowed for 4 hours after which a standard lunch was served. Mean peak theophylline serum levels (C max) was 6.69 mcg/mL and mean time of peak serum concentration (T ... In patients with high theophylline clearance and half-lives of about 4 to 5 hours, such as children age 1 to 9 years, the trough serum ...

WebAug 31, 2024 · high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor. Serious side effects may be more likely in older adults. Common side effects … WebJul 26, 2024 · Too high: 20 to 25 µg/mL: Decrease doses by about 10% and recheck serum level after 3 days. 25 to 30 pg/mL: ... Serum levels should be monitored periodically to determine the theophylline level associated with observed clinical response and to identify the potential for toxicity. For such measurements, the serum sample should be obtained …

WebAug 31, 2024 · High-risk cases include the following: Acute overdose with theophylline levels higher than 80 mcg/mL Chronic toxicity with levels higher than 40 mcg/mL Patients …

WebMar 18, 2010 · Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2-agonists became more widely used.

WebToo much theophylline can be life-threatening. Symptoms of too much theophylline include: Vomiting, heartburn, and belly pain. Rapid heart rate or other changes in heart rhythm. … simple white frosting for cookiesWebJan 14, 2024 · Check with your doctor immediately if any of the following side effects occur while taking theophylline: Incidence not known Chest pain or discomfort dizziness fainting fast, slow, or irregular heartbeat increase in urine volume lightheadedness persistent vomiting pounding or rapid pulse seizures shakiness rayleigh specsaversWebPurpose: To evaluate prospectively whether serum theophylline concentrations of 25 mg/L and greater were predictable (and presumably preventable) by use of basic pharmacokinetic calculations. Design: Prospective study. Patients: Fifty-five patients with a serum theophylline concentration of at least 25.0 mg/L were evaluated initially and if subsequent … simple white frosting for cakeWebMany factors affect the rate of theophylline metabolism. Concentrations are increased in heart failure, cirrhosis, viral infections and in the elderly, and decreased in smokers, … rayleigh sound and visionWebTheophylline interacts with many drugs including: Beta-2 agonists, corticosteroids, diuretics — potentially serious hypokalaemia may result from beta-2 agonist therapy. Check serum … rayleigh spicy menuWebB. Estimate Mr B’s theophylline level at the time of fitting C. How long after stopping Nuelin will Mr B’s theophylline be within the therapeutic range? [Population data: clearance = 0.04 L/hr/kg & volume of distribution = 0.48 L/kg. CHF reduces theophylline clearance by 50%. F … simple white gold braceletWebJul 18, 2024 · In high doses, theophylline can cause irritability, tremors and seizures as well as tachycardia, cardiac arrhythmias and sudden death. With the development of safer, better tolerated and more effective inhaled … simple white gold diamond ring