Definition of lipophilic
WebLipophilic definition: having an affinity for lipids Meaning, pronunciation, translations and examples Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. Such non-polar solvents are themselves lipophilic (translated as "fat-loving" or "fat-liking" ), and the axiom that "like dissolves like" generally holds true. Thus lipophilic substances tend to dissolve in other lipophilic substances, but hydrophilic ("water-loving") substances tend to dissolve in water and ot…
Definition of lipophilic
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WebThe drug is highly lipophilic and able to cross the blood brain barrier at higher doses. From Wikipedia Sulbutiamine overcomes the poor oral bioavailability of thiamine because it is … WebDefinition: Lipophilic or 'lipid-loving' molecules are attracted to lipids. A substance is lipophilic if it is able to dissolve much more easily in lipid (a class of oily organic …
WebOther articles where lipophilicity is discussed: surfactant: hydrophilic (water-soluble) and partly lipophilic (soluble in lipids, or oils). It concentrates at the interfaces between bodies or droplets of water and those of oil, or lipids, … WebLipophilicity is an important physicochemical parameter to link membrane permeability and, drug absorption and distribution with the route of clearance (metabolic or renal). Measuring the compound lipophilicity is readily amenable to automation.
WebMay 2, 2015 · HLB Value and Calculation HLB; According to Griffin, the amphiphilic molecule is the value obtained by dividing the weight percentage of the hydrophilic part by five. There is a balance between ... WebLipophilicity synonyms, Lipophilicity pronunciation, Lipophilicity translation, English dictionary definition of Lipophilicity. adj. Soluble in fats or fat solvents. American Heritage® …
WebFeb 7, 2024 · The lipophilic section is usually a hydrocarbon moiety, consisting of carbon and hydrogen atoms. Lipophilic portions are hydrophobic and nonpolar. The hydrophilic group can be charged or … raspored pogreba vukovarWebNov 8, 2024 · Lipophilicity is a measure for the tendency of a compound to partition into nonpolar (organic) solvent (versus aqueous solvent). Most small molecules/ions need the assistance of specific protein channels to transport them through the cell membrane. These inside-out protein channels are called transporters. dr putzeys kortrijkWebDefinition of lipophilic Literally "fat-loving". Applied to molecular entities (or parts of molecular entities) having a tendency to dissolve in fat-like (e.g. hydrocarbon) solvents. dr putz bankuti grazWeblipophilic: ( lip'ō-fil'ik ), Capable of dissolving, of being dissolved in, or of absorbing lipids. raspored pokopa urbanizamWebAug 7, 2012 · Since lipophilicity is a key determinant in BBB permeability, lipidization, that is, conversion of the drug moiety into a more lipophilic form by the insertion of … dr putty\u0027sWebMar 6, 2024 · Cholesterol is a lipophilic molecule that is essential for human life. It has many roles that contribute to normally functioning cells. For example, cholesterol is an important component of the cell … raspored prijevozaWebWiktionary (0.00 / 0 votes) Rate this definition: lipophilic adjective. Having the quality of dissolving in lipids. lipophilic adjective. Typically have the quality of being composed of … raspored polaganja vozackog ispita